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A new study suggests that prescription drugs like Viagra, Cialis, and Levitra may be able to prevent men who have erectile dysfunction from seeking help to get or keep an erection. They may also increase their odds of getting erections in other areas of the body.

Men who take prescription-only ED drugs or other oral ED drugs, like Cialis or Viagra, may experience increased odds of getting erections in areas of the body with the least amount of blood flow.

Cialis and Viagra both increase blood flow to the penis, and patients who take the drugs may also be able to get erections. The study involved men from Singapore's National Health System, which covers a large variety of healthcare systems.

However, the results of the trial were not conclusive enough to recommend that such drugs be taken with other health conditions.

The National Health System in Singapore is the leading medical research center for Singapore's Ministry of Health and Longs Health, the National Social Science Organisation, and the Singapore General Hospital. It has a long history of collaboration with government agencies and research institutions, including the National Health System.

It also has a special role in helping to manage sexually transmitted diseases, including HIV, Hepatitis B, gonorrhea, syphilis and chlamydia.

For the study, research nurse Dr S S Shing, a member of the study team, and a pharmacist, took part in the trial.

This was followed by a separate investigation by the researchers. This resulted in a significant difference between the treatment groups in the area of blood flow to the penis.

Dr S Shing noted that the researchers also compared the blood flow to the penis with those who took Viagra and Cialis. The blood flow was higher in the Viagra group and the Cialis group.

"The results showed that the blood flow to the penis was more in the Viagra group than in the Cialis group," he said.

It was also important to note that a higher blood flow to the penis could result in an erection. It is not yet known whether the blood flow to the penis increased with a higher dose of ED drugs.

The researchers also analyzed data from patients who had taken Viagra, Cialis, or other oral ED drugs and who also had other health conditions.

They found that the blood flow to the penis increased with the number of people taking these drugs. However, the researchers did not see any changes in blood flow to the penis in these patients.

"Our results were in line with other studies which have shown that taking an ED drug can increase blood flow to the penis and result in an erection," said Dr S Shing.

Dr S Shing added that a larger study was needed to confirm these findings.

"It is important to note that this study did not provide any information on the long-term effects of taking ED drugs or other oral ED drugs," he said.

He recommended that further research into the impact of these drugs be conducted and that men with other health conditions be given the same information as the researchers who took the ED drugs.

"The results of this study should also be considered for use in other studies and in combination with other health conditions," he said.

A review of the scientific literature published in the last nine years in theJournal of Sexual Medicinehad found that the number of men who developed erections in the group who took ED drugs was higher than those who took other drugs.

"We found that the number of men who took ED drugs in the group who used other drugs was significantly higher than the number who took ED drugs in the group who took only ED drugs," said Dr Shing.

The researchers also compared the blood flow to the penis with that of those who did not take ED drugs and also with that of those who used ED drugs.

Dr S Shing noted that the researchers did not directly compare the blood flow to the penis in patients who were taking ED drugs. However, he suggested that patients who were taking the drugs in combination with other health conditions could benefit from further research.

The U. S. Food and Drug Administration (FDA) has released a voluntary recall of approximately 4,500 milligram doses of the generic tadalafil, which is used for the treatment of erectile dysfunction in men. The generic tadalafil is sold under the brand name Cialis.

The FDA has issued a voluntary recall for tadalafil 5mg, which is not approved for the treatment of erectile dysfunction, and the tadalafil 20mg and 40mg are not approved for the treatment of benign prostatic hyperplasia (enlarged prostate).

The recall is for the following products:

  • Tadalafil and Cialis (20mg) 20 tablets;
  • Cialis (10mg) CIALIS® (10mg Cialis extended-release tablet);
  • Cialis (20mg) CIALIS® (20mg Cialis extended-release tablet);

These products were not included in the FDA’s voluntary recall.

The product has not been recalled for being defective. This product may contain active ingredient ingredients or filler ingredients that are different from tadalafil, including microcrystalline cellulose, magnesium stearate, croscarmellose sodium, povidone, and stearic acid.

FDA alert

“Based on the information provided, FDA recommends that consumers do not consume this product to treat erectile dysfunction,” the FDA said in a news release. “FDA is advising consumers not to consume this product to treat erectile dysfunction in men.”

A similar recall was issued by GlaxoSmithKline in the United States following its recall of tadalafil 5mg, which was not approved for the treatment of erectile dysfunction.

The company said the tadalafil is not approved for the treatment of benign prostatic hyperplasia (enlarged prostate).

The company is notifying consumers about its recall.

FDA says the tadalafil is available for sale online at the pharmacy.

For more information, visit www.fda.gov/medwatch or call 1-800-332-1088 to place an order. FDA will respond to this release by December 31, 2017.

Originally published byThe Associated Press

Read More 1.6 million Americans are affected by erectile dysfunction (E. D.)

A study published in the Journal of the American Medical Association in June found that more than half of men were experiencing erectile dysfunction. About 70% were in moderate-to-severe distress.

According to the study, over half of those surveyed said they had difficulty getting or maintaining an erection, and over half said they had experienced a loss of sexual desire in the past year.

More than 23 million American adults have experienced erectile dysfunction.

Copyright © 2025All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.The Associated Press is solely responsible for any accuracy, reliability, and currency. The AP is not liable for any direct, indirect, and/or otherwise applicable loss or damage from any source in the United States or any applicable country.All material may not be posted to or redistributed by the AP.

All material may not be posted to or agreed to by the AP.

Cialis Dosage & Drug interactions

The Cialis is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia, and pulmonary arterial hypertension. It works by relaxing blood vessels in the penis, allowing more blood to flow into the area during sexual arousal.

What is Cialis?

The active ingredient of Cialis is tadalafil. This medication is used to treat erectile dysfunction (ED), which is a condition where a man cannot get or keep an erection long enough to perform sexual activity. It works by increasing blood flow to the penis, which can cause an erection during sexual stimulation.

How Does Cialis Work?

The mechanism of action of Cialis revolves around its ability to increase blood flow to the penis, allowing men to achieve and sustain an erection when sexually stimulated. This mechanism is crucial for improving overall sexual health and quality of life.

Common Drug Interactions with Cialis

As mentioned earlier, Cialis is a medication commonly used to treat erectile dysfunction. However, there are some potential drug interactions that can occur with this medication. Here are some common drug interactions that can occur with Cialis:

Nitrates

Nitrates are often prescribed to treat chest pain or heart conditions. They can cause a sudden drop in blood pressure when combined with Cialis. This can lead to a dangerous drop in blood pressure when taken concurrently.

Alpha Blockers

Alpha blockers are often prescribed to lower blood pressure and to help with ED when combined with Cialis. They can cause a sudden drop in blood pressure when taken with Cialis.

Other Drug Interactions

While Cialis is generally safe and effective when used as directed, there are some potential drug interactions that can occur with other medications that may interact with Cialis.

Drug-Drug Interactions

In addition to drug interactions, there are also other factors that should be considered when considering the use of Cialis.

Interaction with Other Medications

Certain medications can interact with Cialis. This includes certain heart medications, certain antibiotics, and some antifungal drugs. It is essential to inform your healthcare provider of all medications and supplements you are currently taking to avoid any potential interactions.

Interaction with Other Drugs

Certain drugs, such as certain antidepressants, can affect the absorption of Cialis. This can result in decreased effectiveness of the medication and increase side effects. It is crucial to disclose all medications, supplements, and herbal products you are taking to your healthcare provider to minimize any potential interactions.

Drug-Food Interactions

Certain foods can interfere with the medication's absorption and effectiveness. For instance, grapefruit or grapefruit juice can affect the effects of Cialis and increase the likelihood of side effects. It is essential to inform your healthcare provider of all foods, supplements, and medications you are currently taking to avoid any potential interactions.

Certain Foods

Certain foods can affect the effectiveness of Cialis and increase the risk of side effects. For instance, grapefruit can interfere with the absorption and effectiveness of Cialis and increase the risk of side effects.

Certain Medications

Certain medications, such as certain antidepressants, can affect the absorption and effectiveness of Cialis. This can lead to decreased effectiveness and increased side effects. It is crucial to inform your healthcare provider of all medications, supplements, and herbal products you are currently taking to avoid any potential interactions.

Foods

For instance, grapefruit can increase the absorption of Cialis and increase the risk of side effects.

Medications

This can lead to decreased effectiveness and increase side effects.

Drug Interactions with Cialis

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Last updated on October 20.